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2009 Innovations in Clinical Research Awards Skip to main content

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2009 Innovations in Clinical Research Awards

Awarded: Jan 01, 2009

$2,430,000 over 3 years

In 2009, the foundation awarded three-year grants of $486,000 each to five early-stage research projects that have the potential to catalyze innovative therapies for sickle cell disease.

2009 ICRA Grantees

James E. Bradner, M.D.
Dana-Farber Cancer Institute
Project name: Selective Inhibition of HDAC1 and HDAC2 in Sickle Cell Disease

Michael M. Dowling, M.D., Ph.D.
University of Texas Southwestern Medical Center at Dallas
Project name: PFAST: Patent Foramen Ovale and Stroke in Sickle Cell Disease

Benjamin L. Ebert, M.D., Ph.D., and Maureen Okam, M.D., M.P.H.
Brigham and Women's Hospital
Project name: Clinical Development of Histone Deacetylase Inhibitors for the Treatment of Sickle Cell Disease

Donald B. Kohn, M.D., and Philip Gregory, Ph.D.
University of California, Los Angeles, and Sangamo Biosciences, Inc.
Project name: ß-globin Gene Correction in Hematopoietic Stem Cells for Sickle Cell Disease

Guillaume Lettre, Ph.D., and Joel N. Hirschhorn, M.D., Ph.D.
Montreal Heart Institute and Children's Hospital Boston
Project name: Whole-exome Re-sequencing in Sickle Cell Disease Patients with Extremely Mild Clinical Courses